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The Role of Lateralisation and Sex on Insular Cortex: 3D Volumetric Analysis
(TUBITAK Scientific & Technical Research Council Turkey, 2021)
Background/aim: The insula has attracted the attention of many neuroimaging studies because of its key role between brain structures. However, the number of studies investigating the effect of sex and laterality on insular ...
miRNA Sequence Analysis in Patients With Kaposi's Sarcoma-Associated Herpesvirus
(Frontiers Media S.A., 2022)
MicroRNAs (miRNAs) are the non-coding RNAs that can both attach to the untranslated and coding sections of target mRNAs, triggering destruction or post-transcriptional alteration. miRNAs regulate various cellular processes ...
High Expression Level of miR-1260 Family in the Peripheral Blood of Patients with Ovarian Carcinoma
(BMC, 2021)
The most common gynecologic cancers detected in women in Turkey are uterine cancer, ovarian cancer, and cervical cancer. These data reported that a mean of 3800 individuals were diagnosed with uterine cancer, 2790 were ...
Volumetric Analysis of the Brain Structures of Children with Down’s Syndrome: A 3D MRI Study
(Ondokuz Mayis Universitesi, 2021)
Down’s syndrome (DS) is one of the most common genetic causes of mental and cognitive retardation. In fact, it results in a number of characteristic neuropsychological and physical symptoms, including mental retardation. ...
Volumetric Measurements of the Subcortical Structures of Healthy Adult Brains in the Turkish Population
(Via Medica Medical, 2021)
Background: The interest in the morphological development of brain structures during childhood and adolescence arises from discussions on subcortical anomalies and sexual dimorphism, from adolescent changes in cognitive ...
Evaluation of BRCA1/2 Gene Mutations in Patients With High-Risk Breast and/or Ovarian Cancer in Turkey
(De Gruyter, 2022)
Objectives To find BRCA1/2 test selection criteria unique to the Turkish population, as well as to provide the BRCA1/2 gene mutation distributions of patient population to the literature. Methods Genetic counseling was ...
Thyroid hormone resistance with succinate dehydrogenase-B gene mutation
(Edizioni Minerva Medica, 2022)
Resistance to thyroid hormone (RTH) is characterized by non-suppressed TSH concentration despite high T4 and/or T3 levels.1 Resistance may develop at any steps in the hormone
receptor binding, signaling, or intracellular ...
Anti-Inflammatory Effects of Melatonin in Rats with Induced Type 2 Diabetes Mellitus
(MDPI, 2022)
Introduction: Insulin resistance is associated with a pro-inflammatory state increasing the risk for complications in patients with type 2 diabetes mellitus (T2DM). In addition to its chronobi-otic effects, the pineal ...
Breast Cancer Subtypes and Prognosis: Answers to Subgroup Classification Questions, Identifying the Worst Subgroup in Our Single-Center Series
(Dove Medical Press Ltd, 2022)
Purpose: Many studies report the triple negative breast cancer (TNBC) as the worst subgroup, as such patients do not benefit from anti-hormonal therapy and human epidermal growth factor receptor 2 (HER2) antagonists. While ...
Identification of candidate genes in a family with cancer overload by whole-exome sequencing
(Turkish National Pediatric Society, 2022)
Background. Approximately 120 out of every 1 million children in the world develop cancer each year. In Turkey, 2500-3000 children are diagnosed with new cancer each year. The causes of childhood cancer have been studied ...