Browsing by Author "Erciyas, Seda Kilic"
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Aberrant miR-3135b and miR-1273g-3p expression in the peripheral blood samples of BRCA1/2 (±) ovarian cancer patients
Tuncer, Seref Bugra); Celik, Betul; Erciyas, Seda Kilic; Erdogan, Ozge Sukruoglu; Pasin, Ozge; Avsar, Mukaddes; Gultaslar, Busra Kurt; Ghafour, Arash Adamnejad; Uyaroglu, Gamze; Odemis, Demet Akdeniz; Yazici, Hulya (Elsevier Ltd, 2024)Ovarian cancer (OC) ranks as the eighth most prevalent malignancy among women globally. The short non-coding RNA molecules, microRNAs (miRNAs) target multiple mRNAs and regulate the gene expression. Here in this study, we ... -
DNA methylation of KIFC1 gene in determination of histological diagnosis, prognosis and metastasis of lung cancer
Celik, Betul; Pasin, Ozge; Sen, Sena; Tuncer, Seref Bugra; Kayim, Zubeyde Yalniz; Erciyas, Seda Kilic; Erdogan, Ozge Sukruoglu; Gultaslar, Busra Kurt; Ghafour, Arash Adamnejad; Yazici, Hulya; Olgac, Necat Vakur (ELSEVIER GMBH, 2023)Background: One of the main features of cancer, especially lung cancer (LC), is abnormal cell division. Abnormal expression of kinesin family member C1 (KIFC1/HSET), which is involved in mitotic cell division and ensures ... -
Germline mutational variants of Turkish ovarian cancer patients suspected of Hereditary Breast and Ovarian Cancer (HBOC) by next-generation sequencing
Tuncer, Seref Bugra; Celik, Betul; Erciyas, Seda Kilic; Erdogan, Ozge Sukruoglu; Gultaslar, Busra Kurt; Odemis, Demet Akdeniz; Avsar, Mukaddes; Sen, Fatma; Saip, Pinar Mualla; Yazici, Hulya (Elsevier GmbH, 2024)Hereditary Breast and Ovarian Cancer (HBOC) syndrome is characterized by an increased risk of developing breast cancer (BC) and ovarian cancer (OC) due to inherited genetic mutations. Understanding the genetic variants ... -
High Expression of miR-218-5p in the Peripheral Blood Stream and Tumor Tissues of Pediatric Patients with Sarcomas
Ozdenoglu, Fazilet Yildiz; Odemis, Demet Akdeniz; Erciyas, Seda Kilic; Tuncer, Seref Bugra; Gultaslar, Busra Kurt; Salduz, Ahmet; Buyukkapu, Sema; Olgac, Necat Vakur; Kebudi, Rejin; Yazici, Hulya (Springer, 2024)Sarcomas are malignant tumors that may metastasize and the course of the disease is highly aggressive in children and young adults. Because of the rare incidence of sarcomas and the heterogeneity of tumors, there is a need ... -
Identification of candidate genes in a family with cancer overload by whole-exome sequencing
Odemis, Demet Akdeniz; Kebudi, Rejin; Hassani, Masoumeh; Celik, Betul; Tuncer, Seref Bugra; Erciyas, Seda Kilic; Erdogan, Ozge Sukruoglu; Bay, Sema Buyukkapu; Yazici, Hulya (Turkish National Pediatric Society, 2022)Background. Approximately 120 out of every 1 million children in the world develop cancer each year. In Turkey, 2500-3000 children are diagnosed with new cancer each year. The causes of childhood cancer have been studied ... -
miR-3653-3p Expression in PBMCs: Unveiling the Diagnostic Potential for Ovarian Cancer
Delek, Fatma Seher Pektopal; Tuncer, Seref Bugra; Odemis, Demet Akdeniz; Erciyas, Seda Kilic; Erdogan, ozge Sukruoglu; Saip, Pinar; Yazici, Hulya (Springer, 2024)Ovarian cancer is typically diagnosed at an advanced stage, recurs early and often, and currently lacks effective treatment. Therefore, overall survival and progression-free survival are relatively short for this disease. ... -
RB1 gene mutations and genetic spectrum in retinoblastoma cases
Odemis, Demet Akdeniz; Kebudi, Rejin; Bayramova, Jamila; Erciyas, Seda Kilic; Turkcan, Gozde Kuru; Tuncer, Seref Bugra; Erdogan, Ozge Sukruoglu; Celik, Betul; Gultaslar, Busra Kurt; Bay, Sema Buyukkapu; Tuncer, Samuray; Yazici, Hulya (LIPPINCOTT WILLIAMS & WILKINS, 2023)The aim of the study was to investigate the frequency and types of mutations on the retinoblastoma gene (RB1 gene) in Turkish population. RB1 gene mutation analysis was performed in a total of 219 individuals (122 probands ... -
RB1 gene mutations and genetic spectrum in retinoblastoma cases
Odemis, Demet Akdeniz; Kebudi, Rejin; Bayramova, Jamila; Erciyas, Seda Kilic; Turkcan, Gozde Kuru; Tuncer, Seref Bugra; Erdogan, Ozge Sukruoglu; Celik, Betul; Gultaslar, Busra Kurt; Bay, Sema Buyukkapu; Tuncer, Samuray; Yazici, Hulya (Lippincott Williams and Wilkins, 2024)The aim of the study was to investigate the frequency and types of mutations on the retinoblastoma gene (RB1 gene) in Turkish population. RB1 gene mutation analysis was performed in a total of 219 individuals (122 probands ... -
RB1 GENE MUTATIONS IN TURKISH PATIENTS WITH RETINOBLASTOMA
Odemis, Demet Akdeniz; Kebudi, Rejin; Erciyas, Seda Kilic; Turkcan, Gozde Kuru; Tuncer, Seref; Erdogan, Ozge Sukruoglu; Bayramova, Jamila; Celik, Betu; Gultaslar, Busra Kurt; Buyukkapu, Sema Bay; Tuncer, Samuray; Yazici, Hulya (WILEY, 2022)RB1 GENE MUTATIONS IN TURKISH PATIENTS WITH RETINOBLASTOMA -
SARKOM PATOGENEZİNDE ETKİLİ OLABİLECEK YENİ ADAY GENLERİN ARAŞTIRILMASI
Ödemiş, Demet Akdeniz; Kebudi, Rejin; Özdenoğlu, Fazilet Yıldız; Çelik, Betül; Tunçer, Şeref Buğra; Erciyas, Seda Kilic; Erdoğan, Özge Şükrüoğlu; Bay, Sema Buyukkapu; Yazıcı, Hülya (İstanbul Üniversitesi, 2023)Amaç: Nükleer tıpta radyonüklit tedavilerde çalışan radyasyon görevlilerinin uzun dönemde maruz kaldığı radyasyon dozlarının belirlenmesi ve rutin olarak yapılan her bir tedavi prosedürünün bu dozlara katkısının belirlenmesi ...