Browsing by Author "Uba, Abdullahi Ibrahim"
Now showing items 1-20 of 32
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Adding New Scientific Evidences on the Pharmaceutical Properties of Pelargonium quercetorum Agnew Extracts by Using In Vitro and In Silico Approaches
Chiavaroli, Annalisa; Libero, Maria Loreta; Di Simone, Simonetta Cristina; Acquaviva, Alessandra; Nilofar, Lucia; Uba, Abdullahi Ibrahim (MDPI, 2023)Pelargonium quercetorum is a medicinal plant traditionally used for treating intestinal worms. In the present study, the chemical composition and bio-pharmacological properties of P. quercetorum extracts were investigated. ... -
Antioxidant, enzyme inhibition, toxicity, and molecular docking analysis of Melaleuca cajuputi leaf extract and fractions
Isah, Musa; Zengin, Gokhan; Wahab, Wan-Nor-Amilah Wan Abdul; Abdullah, Hasmah; Sul’ain, Mohd Dasuki; Uba, Abdullahi Ibrahim (Visagaa Publishing House, 2024)Melaleuca cajuputi plant has piqued the interest of researchers due to its pharmacological properties. However, there is scarce information regarding its enzyme inhibitory effects and possible mechanism of action. Thus, ... -
Appraisals on the chemical characterization and biological potentials of Ranunculus constantinopolitanus extracts using chromatographic, computational, and molecular network approaches
Uba, Abdullahi Ibrahim; BESIII Collaboration (Elsevier Ltd, 2023)In this context, phytochemicals were extracted from Ranunculus constantinopolitanus using ethyl acetate (EA), ethanol, ethanol/water (70%), and water solvent. The analysis encompassed quantification of total phenolic and ... -
Assessing the Chemical Profile and Biological Potentials of Tamarix aphylla (L.) H.Karst. and Tamarix senegalensis DC. by In Vitro, In Silico, and Network Methodologies
Mahadi, Tawsol M.; Yagi, Sakina; Nilofar; Caprioli, Giovanni; Piatti, Diletta; Ricciutelli, Massimo; Uba, Abdullahi Ibrahim; Ponniya, Sathish Kumar M.; Eltigani, Sayadat M.; Zengin, Gokhan (Springer, 2024)The present study aimed to investigate the chemical profile, antioxidant, and enzyme inhibition properties of extracts from fruits and aerial parts (leaves and twigs) of Tamarix aphylla and T. senegalensis. Hexane, ... -
Bacteriophage genome engineering for phage therapy to combat bacterial antimicrobial resistance as an alternative to antibiotics
Usman, Sani Sharif; Uba, Abdullahi Ibrahim; Christina, Evangeline (SPRINGER, 2023)Bacteriophages (phages) are viruses that mainly infect bacteria and are ubiquitously distributed in nature, especially to their host. Phage engineering involves nucleic acids manipulation of phage genome for antimicrobial ... -
Biological, computational evaluation of novel benzofuranyl derivatives as acetylcholinesterase and butyrylcholinesterase
Usanmaz, Hande; Tas, Omer; Ekinci, Deniz; Uba, Abdullahi Ibrahim; Atmaca, Ufuk (Taylor and Francis Ltd., 2024)Aim: A highly efficient one-step method has been developed for the synthesis of benzofuranyl derivatives from 2-benzoylcyclohexane-1-carboxylic acid derivatives using chlorosulfonyl isocyanate. This novel method provides ... -
Chemical characterization and biological abilities of Anthocleista djalonensis collected from two locations of Ivory Coast
Sinan, Kouadio Ibrahime; Zengin, Gokhan; Uba, Abdullahi Ibrahim; Caprioli, Giovanni; Angeloni, Simone; Vittori, Sauro; Jugreet, Sharmeen; Etienne, Ouattara Katinan; Shariati, Mohamad Ali; Mahomoodally, Mohamad Fawzi (John Wiley and Sons Inc, 2023)In this study, the total phenolic and flavonoid contents, HPLC-DAD detected phytochemicals, antioxidant and enzyme inhibitory potential of methanolic and aqueous (as infusion) extracts of the medicinal plant, Anthocleista ... -
Chemical Characterization of Different Extracts from Artemisia annua and Their Antioxidant, Enzyme Inhibitory and Anti-Inflammatory Properties
Acquaviva, Alessandra; Nilofar; Bouyahya, Abdelhakim; Zengin, Gokhan; Di Simone, Simonetta Cristina; Recinella, Lucia; Leone, Sheila; Brunetti, Luigi; Uba, Abdullahi Ibrahim; Cakilcioğlu, Ugur; Polat, Rıdvan; Darendelioglu, Ekrem (John Wiley and Sons Inc, 2023)Artemisia annua L. (Asteraceae Family) is an important plant in Asia that has been used for treating different diseases, including fever due to malaria, wounds, tubercolisis, scabues, pain, convulsions, diabetes, and ... -
Chemical characterization of Glaucosciadum cordifolium extracts obtained by different extraction techniques and their biopharmaceutical effects
Kljakic, Aleksandra Cvetanovic; Bozunovic, Jelena; Gasic, Uros; Seebaluck-Sandoram, Roumita; Uba, Abdullahi Ibrahim; Mahomoodally, Mohamad Fawzi; Yildiztugay, Evren; Zengin, Gokhan (Elsevier Ltd, 2023)Glaucosciadium cordifolium (Apiaceae) is traditionally used against stomach ailments, as aphrodisiac and appetizer. This study endeavored to characterize several extracts of G. cordifolium aerial parts (prepared by various ... -
Chemical characterization of three different extracts obtained from Chelidonium majus L. (Greater celandine) with insights into their in vitro, in silico and network pharmacological properties
Terzic, Milena; Fayez, Shaimaa; Fahmy, Nouran M.; Eldahshan, Omayma A.; Uba, Abdullahi Ibrahim; Ponniya, Sathish Kumar M.; Selvi, Selami; Nilofar; Koyuncu, Ismail; Yuksekdag, Ozgur; Zengin, Gokhan (Elsevier B.V., 2024)Plant species C. majus, which is a very rich source of secondary metabolites, was used to obtain extracts, using a conventional extraction technique. For the extraction of bioactive molecules, three solvents were used: ... -
Chemical exploration of different extracts from Phytolacca americana leaves and their potential utilization for global health problems: ın silico and network pharmacology validation
Uba, Abdullahi Ibrahim; BESIII Collaboration (Taylor and Francis Ltd., 2024)Phytolacca americana L. is of great interest as a traditional additive in various folk remedies in several countries, including Turkey. We aimed to determine the chemical profile (assisted by high-Performance liquid ... -
Combining chemical profiles and biological abilities of different extracts from Tanacetum nitens ( Boiss. & NoE) Grierson using network pharmacology
Dall'Acqua, Stefano; Yagi, Sakina; Sut, Stefania; Uba, Abdullahi Ibrahim; Ponniya, Sathish Kumar M.; Koyuncu, Ismail; Toprak, Kenan; Balos, Mehmet Maruf; Kaplan, Alevcan; Cakilcioglu, Ugur; Zengin, Gokhan (John Wiley and Sons Inc, 2024)Tanacetum nitens ( Boiss. & No & euml;) Grierson is an aromatic perennial herb used in Turkish traditional medicine to treat headache, fever, and skin diseases. This study aimed to investigate the chemical composition, ... -
Combining chemical profiles and biological abilities of different extracts from Tanacetum nitens ( Boiss. & NoE) Grierson using network pharmacology
Dall'Acqua, Stefano; Yagi, Sakina; Sut, Stefania; Uba, Abdullahi Ibrahim; Yildiztugay, Evren; Koyuncu, Ismail; Yuksekdag, Ozgur; Ponniya, Sathish Kumar M.; Jayavel, Ashokkumar; Zengin, Gokhan (WILEY-V C H VERLAG GMBH, 2024)Tanacetum nitens ( Boiss. & No & euml;) Grierson is an aromatic perennial herb used in Turkish traditional medicine to treat headache, fever, and skin diseases. This study aimed to investigate the chemical composition, ... -
Comparative GC-MS Analysis of Fresh and Dried Curcuma Essential Oils with Insights into Their Antioxidant and Enzyme Inhibitory Activities
Fahmy, Nouran M.; Fayez, Shaimaa; Uba, Abdullahi Ibrahim; Shariati, Mohammad Ali; Aljohani, Abdullah S. M.; El-Ashmawy, Ibrahim M.; Batiha, Gaber El-Saber; Eldahshan, Omayma A.; Singab, Abdel Nasser; Zengin, Gokhan (MDPI, 2023)Species belonging to the Zingiberaceae family are of high nutritional, industrial, and medicinal values. In this study, we investigated the effect of processing steps (fresh vs. dried milled rhizomes) and extraction ... -
A comparative study on chemical profiles and biological activities of different extracts of three Verbascum species from Turkey
Zengin, Gokhan; Yagi, Sakina; Kopjar, Mirela; Yildiztugay, Evren; Ćorković, Ina; Kumar, Sathish; Rengasamy, Kannan RR; AlDhaheri, Yusra; Eid, Ali H.; Uba, Abdullahi Ibrahim (ELSEVIER, 2023)The present study aimed to evaluate the antioxidant and enzyme inhibition properties of aerial part of Verbascum cheiranthifolium Boiss. V. myriocarpum Boiss. & Heldr. and V. pyroliforme (Boiss. & Heldr.) Kuntze as well ... -
Comparative Study on the Chemical Profile, Antioxidant Activity, and Enzyme Inhibition Capacity of Red and White Hibiscus sabdariffa Variety Calyces
Yagi, Sakina; Uba, Abdullahi Ibrahim; Sinan, Kouadio Ibrahime; Piatti, Diletta; Sagratini, Gianni; Caprioli, Giovanni; Eltigani, Sayadat M.; Lazarova, Irina; Zengin, Gokhan (American Chemical Society, 2023)Hibiscus sabdariffa L. (Family: Malvaceae) is believed to be domesticated by the people of western Sudan sometime before 4000 BC for their nutritional and medicinal properties. This study aimed to investigate the chemical ... -
Computational analysis of drug resistance of taxanes bound to human β-tubulin mutant (D26E)
Uba, Abdullahi Ibrahim; Bui-Linh, Candice; Thornton, Julianne M.; Olivieri, Michael; Wu, Chun (Elsevier Inc., 2023)The single-point mutation D26E in human β-tubulin is associated with drug resistance seen with two anti-mitotic taxanes (paclitaxel and docetaxel) when used to treat cancers. The molecular mechanism of this resistance ... -
Elucidating the chemical profile and biological studies of Verbascum diversifolium Hochst. extracts
Uba, Abdullahi Ibrahim; BESIII Collaboration (Frontiers Media SA, 2024)The present study was designed to evaluate the chemical composition, antioxidant, enzyme inhibition and cytotoxic properties of different extracts from aerial parts of V. diversifolium (family Scrophulariaceae), a plant ... -
Exploring Chemical Composition, Antioxidant, Enzyme Inhibitory and Cytotoxic Properties of Glaucium acutidentatum Hausskn. & Bornm. from Turkey Flora
Yagi, Sakina; Zengin, Gokhan; Uba, Abdullahi Ibrahim; Maciejewska-Turska, Magdalena; Sieniawska, Elwira; Swiatek, Lukasz; Rajtar, Barbara; Guler, Osman; Dall'Acqua, Stefano (MDPI, 2024)The present study was performed to determine the chemical constituents, cytotoxicity, antioxidant and enzyme inhibition activities of the aerial parts of Glaucium acutidentatum Hausskn. and Bornm. (family Papaveraceae). ... -
Exploring the composition and potential uses of four hops varieties through different extraction techniques
Kljakic, Aleksandra Cvetanovic; Ocvirk, Miha; Rutnik, Ksenija; Kosir, Iztok Joze; Pavlic, Branimir; Maskovic, Pavle; Maskovic, Jelena; Teslic, Nemanja; Stupar, Alena; Uba, Abdullahi Ibrahim; Zengin, Gokhan (Elsevier Ltd, 2024)Hydrophilic, lipophilic extracts and essential oil of four hops varieties from Slovenia were examined in this study. Lipophilic extracts were obtained by supercritical extraction (SFE), while for hydrophilic extracts ...