Browsing by Author "Zengin, Gokhan"
Now showing items 1-20 of 28
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Antioxidant, enzyme inhibition, toxicity, and molecular docking analysis of Melaleuca cajuputi leaf extract and fractions
Isah, Musa; Zengin, Gokhan; Wahab, Wan-Nor-Amilah Wan Abdul; Abdullah, Hasmah; Sul’ain, Mohd Dasuki; Uba, Abdullahi Ibrahim (Visagaa Publishing House, 2024)Melaleuca cajuputi plant has piqued the interest of researchers due to its pharmacological properties. However, there is scarce information regarding its enzyme inhibitory effects and possible mechanism of action. Thus, ... -
Assessing the Chemical Profile and Biological Potentials of Tamarix aphylla (L.) H.Karst. and Tamarix senegalensis DC. by In Vitro, In Silico, and Network Methodologies
Mahadi, Tawsol M.; Yagi, Sakina; Nilofar; Caprioli, Giovanni; Piatti, Diletta; Ricciutelli, Massimo; Uba, Abdullahi Ibrahim; Ponniya, Sathish Kumar M.; Eltigani, Sayadat M.; Zengin, Gokhan (Springer, 2024)The present study aimed to investigate the chemical profile, antioxidant, and enzyme inhibition properties of extracts from fruits and aerial parts (leaves and twigs) of Tamarix aphylla and T. senegalensis. Hexane, ... -
Bioactive agents from Parkia biglobosa (Jacq.) R.Br. ex G. Don bark extracts for health promotion and nutraceutical uses
Sut, Stefania; Dall'Acqua, Stefano; Sinan, Kouadio Ibrahime; Zengin, Gokhan; Uba, Abdullah Ibrahim; Etienne, Ouattara Katinan; Jugreet, Sharmeen; Mahomoodally, Mohamad Fawzi (John Wiley and Sons Ltd, 2024)Background: Parkia biglobosa stem bark extracts were prepared using methanol, methanol 80%, water and ethyl acetate to investigate their phytochemical contents, as well as antioxidant and enzyme inhibitory properties.Results: ... -
Chemical characterization and biological abilities of Anthocleista djalonensis collected from two locations of Ivory Coast
Sinan, Kouadio Ibrahime; Zengin, Gokhan; Uba, Abdullahi Ibrahim; Caprioli, Giovanni; Angeloni, Simone; Vittori, Sauro; Jugreet, Sharmeen; Etienne, Ouattara Katinan; Shariati, Mohamad Ali; Mahomoodally, Mohamad Fawzi (John Wiley and Sons Inc, 2023)In this study, the total phenolic and flavonoid contents, HPLC-DAD detected phytochemicals, antioxidant and enzyme inhibitory potential of methanolic and aqueous (as infusion) extracts of the medicinal plant, Anthocleista ... -
Chemical Characterization and Multidirectional Biological Effects of Different Solvent Extracts of Arum elongatum: in Vitro and in Silico Approaches
Fawzi Mahomoodally, Mohamad; Zengin, Gokhan; Roumita, Seebaluck-Sandoram; Caprioli, Giovanni; Mustafa, Ahmed M.; Piatti, Diletta; Yildiztugay, Evren; Ak, Gunes; Esra Karadag, Ayse; Khalid, Asaad; Abdalla, Ashraf N.; Ibrahim Uba, Abdullahi; Demirci, Fatih (WILEY-V C H VERLAG GMBH, 2023)Arum elongatum (Araceae) is widely used traditionally for the treatment of abdominal pain, arterial hypertension, diabetes mellitus, rheumatism and hemorrhoids. This study investigated the antioxidant properties, individual ... -
Chemical Characterization of Different Extracts from Artemisia annua and Their Antioxidant, Enzyme Inhibitory and Anti-Inflammatory Properties
Acquaviva, Alessandra; Nilofar; Bouyahya, Abdelhakim; Zengin, Gokhan; Di Simone, Simonetta Cristina; Recinella, Lucia; Leone, Sheila; Brunetti, Luigi; Uba, Abdullahi Ibrahim; Cakilcioğlu, Ugur; Polat, Rıdvan; Darendelioglu, Ekrem (John Wiley and Sons Inc, 2023)Artemisia annua L. (Asteraceae Family) is an important plant in Asia that has been used for treating different diseases, including fever due to malaria, wounds, tubercolisis, scabues, pain, convulsions, diabetes, and ... -
Chemical characterization of Glaucosciadum cordifolium extracts obtained by different extraction techniques and their biopharmaceutical effects
Kljakic, Aleksandra Cvetanovic; Bozunovic, Jelena; Gasic, Uros; Seebaluck-Sandoram, Roumita; Uba, Abdullahi Ibrahim; Mahomoodally, Mohamad Fawzi; Yildiztugay, Evren; Zengin, Gokhan (Elsevier Ltd, 2023)Glaucosciadium cordifolium (Apiaceae) is traditionally used against stomach ailments, as aphrodisiac and appetizer. This study endeavored to characterize several extracts of G. cordifolium aerial parts (prepared by various ... -
Chemical characterization of three different extracts obtained from Chelidonium majus L. (Greater celandine) with insights into their in vitro, in silico and network pharmacological properties
Terzic, Milena; Fayez, Shaimaa; Fahmy, Nouran M.; Eldahshan, Omayma A.; Uba, Abdullahi Ibrahim; Ponniya, Sathish Kumar M.; Selvi, Selami; Nilofar; Koyuncu, Ismail; Yuksekdag, Ozgur; Zengin, Gokhan (Elsevier B.V., 2024)Plant species C. majus, which is a very rich source of secondary metabolites, was used to obtain extracts, using a conventional extraction technique. For the extraction of bioactive molecules, three solvents were used: ... -
Combining chemical profiles and biological abilities of different extracts from Tanacetum nitens ( Boiss. & NoE) Grierson using network pharmacology
Dall'Acqua, Stefano; Yagi, Sakina; Sut, Stefania; Uba, Abdullahi Ibrahim; Ponniya, Sathish Kumar M.; Koyuncu, Ismail; Toprak, Kenan; Balos, Mehmet Maruf; Kaplan, Alevcan; Cakilcioglu, Ugur; Zengin, Gokhan (John Wiley and Sons Inc, 2024)Tanacetum nitens ( Boiss. & No & euml;) Grierson is an aromatic perennial herb used in Turkish traditional medicine to treat headache, fever, and skin diseases. This study aimed to investigate the chemical composition, ... -
Combining chemical profiles and biological abilities of different extracts from Tanacetum nitens ( Boiss. & NoE) Grierson using network pharmacology
Dall'Acqua, Stefano; Yagi, Sakina; Sut, Stefania; Uba, Abdullahi Ibrahim; Yildiztugay, Evren; Koyuncu, Ismail; Yuksekdag, Ozgur; Ponniya, Sathish Kumar M.; Jayavel, Ashokkumar; Zengin, Gokhan (WILEY-V C H VERLAG GMBH, 2024)Tanacetum nitens ( Boiss. & No & euml;) Grierson is an aromatic perennial herb used in Turkish traditional medicine to treat headache, fever, and skin diseases. This study aimed to investigate the chemical composition, ... -
Comparative GC-MS Analysis of Fresh and Dried Curcuma Essential Oils with Insights into Their Antioxidant and Enzyme Inhibitory Activities
Fahmy, Nouran M.; Fayez, Shaimaa; Uba, Abdullahi Ibrahim; Shariati, Mohammad Ali; Aljohani, Abdullah S. M.; El-Ashmawy, Ibrahim M.; Batiha, Gaber El-Saber; Eldahshan, Omayma A.; Singab, Abdel Nasser; Zengin, Gokhan (MDPI, 2023)Species belonging to the Zingiberaceae family are of high nutritional, industrial, and medicinal values. In this study, we investigated the effect of processing steps (fresh vs. dried milled rhizomes) and extraction ... -
A comparative study on chemical profiles and biological activities of different extracts of three Verbascum species from Turkey
Zengin, Gokhan; Yagi, Sakina; Kopjar, Mirela; Yildiztugay, Evren; Ćorković, Ina; Kumar, Sathish; Rengasamy, Kannan RR; AlDhaheri, Yusra; Eid, Ali H.; Uba, Abdullahi Ibrahim (ELSEVIER, 2023)The present study aimed to evaluate the antioxidant and enzyme inhibition properties of aerial part of Verbascum cheiranthifolium Boiss. V. myriocarpum Boiss. & Heldr. and V. pyroliforme (Boiss. & Heldr.) Kuntze as well ... -
Comparative Study on the Chemical Profile, Antioxidant Activity, and Enzyme Inhibition Capacity of Red and White Hibiscus sabdariffa Variety Calyces
Yagi, Sakina; Uba, Abdullahi Ibrahim; Sinan, Kouadio Ibrahime; Piatti, Diletta; Sagratini, Gianni; Caprioli, Giovanni; Eltigani, Sayadat M.; Lazarova, Irina; Zengin, Gokhan (American Chemical Society, 2023)Hibiscus sabdariffa L. (Family: Malvaceae) is believed to be domesticated by the people of western Sudan sometime before 4000 BC for their nutritional and medicinal properties. This study aimed to investigate the chemical ... -
Exploring Chemical Composition, Antioxidant, Enzyme Inhibitory and Cytotoxic Properties of Glaucium acutidentatum Hausskn. & Bornm. from Turkey Flora
Yagi, Sakina; Zengin, Gokhan; Uba, Abdullahi Ibrahim; Maciejewska-Turska, Magdalena; Sieniawska, Elwira; Swiatek, Lukasz; Rajtar, Barbara; Guler, Osman; Dall'Acqua, Stefano (MDPI, 2024)The present study was performed to determine the chemical constituents, cytotoxicity, antioxidant and enzyme inhibition activities of the aerial parts of Glaucium acutidentatum Hausskn. and Bornm. (family Papaveraceae). ... -
Exploring the composition and potential uses of four hops varieties through different extraction techniques
Kljakic, Aleksandra Cvetanovic; Ocvirk, Miha; Rutnik, Ksenija; Kosir, Iztok Joze; Pavlic, Branimir; Maskovic, Pavle; Maskovic, Jelena; Teslic, Nemanja; Stupar, Alena; Uba, Abdullahi Ibrahim; Zengin, Gokhan (Elsevier Ltd, 2024)Hydrophilic, lipophilic extracts and essential oil of four hops varieties from Slovenia were examined in this study. Lipophilic extracts were obtained by supercritical extraction (SFE), while for hydrophilic extracts ... -
Extractions of aerial parts of Hippomarathrum scabrum with conventional and green methodologies
Duran, Tugce; Uba, Abdullahi Ibrahim; Nilofar; Cvetanović Kljakić, Aleksandra; Božunović, Jelena; Gašić, Uroš; Bouyahya, Abdelhakim; Yıldiztugay, Evren; Ferrante, Claudio; Zengin, Gokhan (John Wiley and Sons Inc, 2023)Hippomarathrum scabrum L. is an endemic medicinal plant in Turkey; however, there have been few studies investigating the phytochemistry and biological properties of these plants has not been investigated. The aim of this ... -
In the quest for histone deacetylase inhibitors: current trends in the application of multilayered computational methods
Zengin, Gokhan (SPRINGER WIEN, 2023)Histone deacetylase (HDAC) inhibitors have gained attention over the past three decades because of their potential in the treatment of different diseases including various forms of cancers, neurodegenerative disorders, ... -
In Vitro and Molecular Docking Evaluation of Larvicidal Effects of Essential Oils of Five Aromatic Plants on the Fall Armyworm Spodoptera frugiperda JE. Smith (Lepidoptera: Noctuidae) from Ivory Coast
Kobenan, Koffi Christophe; Kouadio, Ibrahime Sinan; Kouakou, Malanno; Silvie, Pierre; Kouadio, Kra Norbert Bini; N'goran, Kouadio Emmanuel; Kouakou, Brou Julien; Amangoua, Nogbou Ferdinand; Tehia, Kouakou Etienne; Uba, Abdullahi Ibrahim; Zengin, Gokhan (WILEY-V C H VERLAG GMBH, 2023)Faced with the serious consequences resulting from the abusive and repeated use of synthetic chemicals, today rethinking crop protection is more than necessary. It is in this context that the essential oils of the Lamiaceae ... -
Integrating chemical analysis with in vitro, in silico, and network pharmacology to discover potential functional compounds from Marrubium astracanicum subsp. macrodon
Avsar, Omer Kaan; Kasbolat, Sevgi; Ak, Gunes; Nilofar; Caprioli, Giovanni; Santanatoglia, Agnese; Uysal, Ahmet; Uba, Abdullahi Ibrahim; Ponniya, Sathish Kumar M.; Paksoy, Mehmet Yavuz; Zengin, Gokhan (Elsevier B.V., 2024)The members of the genus Marrubium are of great interest because they contain biologically active compounds. With in this mind, we aimed to examine the chemical profiles and biological activities (antioxidant, enzyme ... -
Integration of chemical characterization, biological activities, and network pharmacology of different extracts from Syzygium rowlandii
Sinan, Kouadio Ibrahime; Sut, Stefania; Zengin, Gokhan; Dall'Acqua, Stefano; Bouyahya, Abdelhakim; Uba, Abdullahi Ibrahim; Ponniya, Sathish Kumar M.; Rengasamy, Kannan R. R. (ELSEVIER, 2024)The leaves and stem barks of Syzygium rowlandii, were considered as sources of biologically active compounds. Using the ultrasound-assisted extraction with different solvents, we obtained three types of extracts (ethyl ...