Efficient synthesis and characterization of novel isoxazole derivatives including dihdyropyrazole and methanoisoindole moieties
Künye
Gurdere, M. B., Erturk, F., Budak, Y., & Ceylan, M. (2020). Efficient synthesis and characterization of novel isoxazole derivatives including dihdyropyrazole and methanoisoindole moieties. Organic Communications, 13(2), 57-64. doi:10.25135/acg.oc.79.20.06.1668Özet
Isoxazole and pyrazole derivatives have a wide range of biological activity and they are of great interest to medicinal chemist. In this study, the synthesis and characterization of a series of novel hybrid molecules containing pyrazole and isoxazole rings ((3aS,4S,4aR,7aS,8S,8aS)-6-(4-(1-acetyl-5-(4-(aryl/heteroaryl))-4,5-dihydro-1H-pyrazol-3-yl)phenyl)-3-methyl-4,4 a,8,8a-tetrahydro-3-aH-4,8-methanoisoxazo-lo [4,5-A isoindole-5,7(6H,7aH)-dione derivatives) were reported.