Güncel Gönderiler: Tıp Fakültesi
Toplam kayıt 103, listelenen: 1-20
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RB1 gene mutations and genetic spectrum in retinoblastoma cases
(Lippincott Williams and Wilkins, 2024)The aim of the study was to investigate the frequency and types of mutations on the retinoblastoma gene (RB1 gene) in Turkish population. RB1 gene mutation analysis was performed in a total of 219 individuals (122 probands ... -
High Expression of miR-218-5p in the Peripheral Blood Stream and Tumor Tissues of Pediatric Patients with Sarcomas
(Springer, 2024)Sarcomas are malignant tumors that may metastasize and the course of the disease is highly aggressive in children and young adults. Because of the rare incidence of sarcomas and the heterogeneity of tumors, there is a need ... -
Comparison of microRNA expression levels in patients with schizophrenia before and after electroconvulsive therapy
(LIPPINCOTT WILLIAMS & WILKINS, 2024)ObjectiveExploring the role of microRNAs in the antipsychotic efficacy of electroconvulsive therapy (ECT) will contribute to understanding the underlying mechanism through which ECT exerts its therapeutic effects. The ... -
The effects of the combination of temozolomide and Eribulin on T98G human glioblastoma cell line
(TAYLOR & FRANCIS INC, 2024)Glioblastoma tumors are the most aggressive primary brain tumors that develop resistance to temozolomide (TMZ). Eribulin (ERB) exhibits a unique mechanism of action by inhibiting microtubule dynamics during the G2/M cell ... -
Genetic Alterations in Lung Cancer
(KARE PUBL, 2024)Lung cancer is the leading cause of cancer -related deaths worldwide. Due to the prevalence of late -stage diagnoses, treatment options are frequently constrained. Molecular profiling of lung cancer is crucial for the ... -
Factors associated with psychological distress during genetic counseling in high-risk women with breast cancer in Turkey
(Springer Science and Business Media Deutschland GmbH, 2024)Purpose This study aims to shed light on the rather neglected area of research of psychological distress in women facing genetic counselling in Turkey, where few institutions providing such counselling exist. Methods 105 ... -
The Relationship between Frontal QRS-T Angle and Vitamin D Deficiency
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Background and Objectives: A deficiency in serum 25-hydroxyvitamin D levels is associated with a number of cardiovascular situations, such as high blood pressure, heart failure, atherosclerotic heart disease, and peripheral ... -
A Visceral Leishmaniasis Case from the Black Sea Region
(GALENOS PUBL HOUSE, 2024)Karadeniz Bölgesinden Bir Visseral Leishmaniasis Olgusu: Deri Lezyonları ve Kemik İliğinde Leishmania donovani Amastigotları. -
Genetic Alterations in Lung Cancer
(KARE PUBL, 2024)Lung cancer is the leading cause of cancer -related deaths worldwide. Due to the prevalence of late -stage diagnoses, treatment options are frequently constrained. Molecular profiling of lung cancer is crucial for the ... -
Subcortical Volume Changes in Schizophrenia and Bipolar Disorder: A Quantitative MRI Study
(Universidad de la Frontera, 2024)Volume abnormalities in subcortical structures, including the hippocampus, amygdala, thalamus, caudate, putamen, and globus pallidus have been observed in schizophrenia (SZ) and bipolar disorder (BD), not all individuals ... -
Evaluation of treatment outcomes and tolerability in older patients with rectal cancer treated with radiotherapy accompanied by the G-8 geriatric score: TROD13-003 multicenter study
(Elsevier Ltd, 2024)Introduction: The choice of treatment for rectal cancer often differs in older and younger patients, with the rate of radiotherapy use lower among older adults. In our daily practice, when evaluating a frail older patient ... -
Propionyl-L-carnitine mitigates ischemia-reperfusion injury in rat epigastric island flaps
(Elsevier Ltd, 2024)Background: Ischemia-reperfusion injury presents a substantial concern in various medical scenarios, notably in reconstructive surgery involving tissue flaps. Despite reports on the protective benefits of Propionyl-L-carnitine ... -
Aberrant miR-3135b and miR-1273g-3p expression in the peripheral blood samples of BRCA1/2 (±) ovarian cancer patients
(Elsevier Ltd, 2024)Ovarian cancer (OC) ranks as the eighth most prevalent malignancy among women globally. The short non-coding RNA molecules, microRNAs (miRNAs) target multiple mRNAs and regulate the gene expression. Here in this study, we ... -
Temporary external skin plication
(Verduci Editore s.r.l, 2024)– OBJECTIVE: The aim of this study was to elucidate the external temporary skin plication (ETSP) technique in gynecomastia surgery and evaluate its role in mitigating complications and enhancing cosmetic outcomes. PATIENTS ... -
Germline mutational variants of Turkish ovarian cancer patients suspected of Hereditary Breast and Ovarian Cancer (HBOC) by next-generation sequencing
(Elsevier GmbH, 2024)Hereditary Breast and Ovarian Cancer (HBOC) syndrome is characterized by an increased risk of developing breast cancer (BC) and ovarian cancer (OC) due to inherited genetic mutations. Understanding the genetic variants ... -
Structural and Functional Changes in the Brains of Guitarist Musicians: Volumetric, VBM, and Resting State fMRI Study
(ERCIYES UNIV SCH MEDICINE, 2024)Objective: Musicians acquire intricate motor and auditory skills from an early age, serving as an exemplary model for brain plasticity. This study aimed to investigate the structural and functional differences in the brains ... -
Angiotensin II Type I Receptor-168A/G Polymorphism Is Associated with Increased the Risk of Glioma in Turkish Population
(Pleiades Publishing, 2024)Abstract: Gliomas are the most common primary tumors of the Central Nervous System. Despite advances in the elucidation of molecular pathogenesis, gliomas still remain incurable. In the study, it was aimed to investigate ... -
Effects of Anatolian Propolis and Hypertonic Saline Combination Nasal Spray on Allergic Rhinitis Symptoms
(SAGE PUBLICATIONS INC, 2024)Objectives: This study aimed to evaluate how Rhinapi nasal spray affects symptoms of allergic rhinitis. Methods: In this prospective, multicenter, observational study, 10,000 patients (comprising 5028 males and 4972 females) ... -
Post-ERCP Pancreatitis Risk Factors: Is Post-Sphincterotomy Bleeding Another Risk Factor?
(Lippincott Williams and Wilkins, 2024)Background: Despite advancements in technology and expertise, ERCP carries risks of significant complications, such as pancreatitis, bleeding, and perforation. Post-ERCP pancreatitis is the most common and important ... -
Heterogeneity of sensitization profiles and clinical phenotypes among patients with seasonal allergic rhinitis in Southern European countries-The @IT.2020 multicenter study
(John Wiley and Sons Inc, 2024)Background: Pollen allergy poses a significant health and economic burden in Europe. Disease patterns are relatively homogeneous within Central and Northern European countries. However, no study broadly assessed the features ...
