Başlık için Temel Tıp Bilimleri Bölümü Makale Koleksiyonu listeleme
Toplam kayıt 50, listelenen: 25-44
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Germline mutational variants of Turkish ovarian cancer patients suspected of Hereditary Breast and Ovarian Cancer (HBOC) by next-generation sequencing
(Elsevier GmbH, 2024)Hereditary Breast and Ovarian Cancer (HBOC) syndrome is characterized by an increased risk of developing breast cancer (BC) and ovarian cancer (OC) due to inherited genetic mutations. Understanding the genetic variants ... -
High Expression Level of miR-1260 Family in the Peripheral Blood of Patients with Ovarian Carcinoma
(BMC, 2021)The most common gynecologic cancers detected in women in Turkey are uterine cancer, ovarian cancer, and cervical cancer. These data reported that a mean of 3800 individuals were diagnosed with uterine cancer, 2790 were ... -
High Expression of miR-218-5p in the Peripheral Blood Stream and Tumor Tissues of Pediatric Patients with Sarcomas
(Springer, 2024)Sarcomas are malignant tumors that may metastasize and the course of the disease is highly aggressive in children and young adults. Because of the rare incidence of sarcomas and the heterogeneity of tumors, there is a need ... -
Histopathological View of Benign Essential Blepharospasm: Orbicularis Oculi Hormone Receptor Levels
(Kare Publishing, 2023)Objectives: Benign essential blepharospasm (BEB) is a focal dystonia characterized by involuntary contractions of the orbicularis oculi and periocular muscles. We aimed to investigate the effects of muscle receptor levels ... -
Identification of candidate genes in a family with cancer overload by whole-exome sequencing
(Turkish National Pediatric Society, 2022)Background. Approximately 120 out of every 1 million children in the world develop cancer each year. In Turkey, 2500-3000 children are diagnosed with new cancer each year. The causes of childhood cancer have been studied ... -
Impact of Cerebral Microbleeds in Stroke Patients with Atrial Fibrillation
(John Wiley and Sons Inc, 2023)Objectives: Cerebral microbleeds are associated with the risks of ischemic stroke and intracranial hemorrhage, causing clinical dilemmas for antithrombotic treatment decisions. We aimed to evaluate the risks of intracranial ... -
Investigation of the methylation changes in the promoter region of RB1 gene in retinoblastoma
(Elsevier GmbH, 2024)Retinoblastoma is an infrequent neoplasm that arises during childhood from retinal nerve cells and is attributed to the biallelic inactivation of the RB1 gene. In conjunction with anatomical anomalies, it is widely ... -
Knowledge levels of prehospital emergency health workers about occupational disease risk factors and influencing factors
(SERNEV Ar-Ge Yazılım Yayıncılık Eğitim Danışmanlık ve Organizasyon Ticaret Limited Şirketi, 2022)Introduction: Today, occupational diseases are growing more and more significant. This study aims to determine pre-hospital health workers' degree of awareness regarding the risk factors they can run into related to ... -
Lactobacillus GG is associated with mucin genes expressions in type 2 diabetes mellitus: a randomized, placebo-controlled trial
(SPRINGER HEIDELBERG, 2023)Purpose Recent studies indicate that dysbiosis of gut microbiota and low-grade infammation are important pathogenic determinants of type two diabetes mellitus (T2DM). The aim of this study is to investigate the efects of ... -
miRNA Sequence Analysis in Patients With Kaposi's Sarcoma-Associated Herpesvirus
(Frontiers Media S.A., 2022)MicroRNAs (miRNAs) are the non-coding RNAs that can both attach to the untranslated and coding sections of target mRNAs, triggering destruction or post-transcriptional alteration. miRNAs regulate various cellular processes ... -
Modulation of Neuronal Damage in DRG by Asprosin in a High-Glucose Environment and Its Impact on miRNA181-a Expression in Diabetic DRG
(Springer, 2024)Asprosin, a hormone secreted from adipose tissue, has been implicated in the modulation of cell viability. Current studies suggest that neurological impairments are increased in individuals with obesity-linked diabetes, ... -
P323L Mutation in a Case with Prolonged SARS-CoV-2 PCR Positivity
(NLM (Medline), 2023)Coronavirus disease-2019 (COVID-19) emerged in the last months of 2019 and caused a pandemic effecting the whole world. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of COVID-19 has ... -
RB1 gene mutations and genetic spectrum in retinoblastoma cases
(LIPPINCOTT WILLIAMS & WILKINS, 2023)The aim of the study was to investigate the frequency and types of mutations on the retinoblastoma gene (RB1 gene) in Turkish population. RB1 gene mutation analysis was performed in a total of 219 individuals (122 probands ... -
RB1 gene mutations and genetic spectrum in retinoblastoma cases
(Lippincott Williams and Wilkins, 2024)The aim of the study was to investigate the frequency and types of mutations on the retinoblastoma gene (RB1 gene) in Turkish population. RB1 gene mutation analysis was performed in a total of 219 individuals (122 probands ... -
The Role of Lateralisation and Sex on Insular Cortex: 3D Volumetric Analysis
(TUBITAK Scientific & Technical Research Council Turkey, 2021)Background/aim: The insula has attracted the attention of many neuroimaging studies because of its key role between brain structures. However, the number of studies investigating the effect of sex and laterality on insular ... -
SARKOM PATOGENEZİNDE ETKİLİ OLABİLECEK YENİ ADAY GENLERİN ARAŞTIRILMASI
(İstanbul Üniversitesi, 2023)Amaç: Nükleer tıpta radyonüklit tedavilerde çalışan radyasyon görevlilerinin uzun dönemde maruz kaldığı radyasyon dozlarının belirlenmesi ve rutin olarak yapılan her bir tedavi prosedürünün bu dozlara katkısının belirlenmesi ... -
Stereological Study on the Effect of Carnosine on of Purkinje Cells in the Cerebellum of Rats Exposed to 900 MHz Electromagnetic Field
(Turkish Neurosurgical Society, 2022)AIM: To evaluate the impact of carnosine on Purkinje neurons in rats exposed to a 900 Mhz electromagnetic field. MATERIAL and METHODS: This study evaluated 24 rats divided into the following three different groups: a control ... -
Stroke Risk and Antithrombotic Treatment During Follow-up of Patients With Ischemic Stroke and Cortical Superficial Siderosis
(LIPPINCOTT WILLIAMS & WILKINS, 2023)Background and ObjectivesIn patients with ischemic stroke (IS) or transient ischemic attack (TIA) and cortical superficial siderosis (cSS), there are few data regarding the risk of future cerebrovascular events and also ... -
Structural and Functional Changes in the Brains of Guitarist Musicians: Volumetric, VBM, and Resting State fMRI Study
(ERCIYES UNIV SCH MEDICINE, 2024)Objective: Musicians acquire intricate motor and auditory skills from an early age, serving as an exemplary model for brain plasticity. This study aimed to investigate the structural and functional differences in the brains ... -
Subcortical Volume Changes in Schizophrenia and Bipolar Disorder: A Quantitative MRI Study
(Universidad de la Frontera, 2024)Volume abnormalities in subcortical structures, including the hippocampus, amygdala, thalamus, caudate, putamen, and globus pallidus have been observed in schizophrenia (SZ) and bipolar disorder (BD), not all individuals ...