• RB1 gene mutations and genetic spectrum in retinoblastoma cases 

  Odemis, Demet Akdeniz; Kebudi, Rejin; Bayramova, Jamila; Erciyas, Seda Kilic; Turkcan, Gozde Kuru; Tuncer, Seref Bugra; Erdogan, Ozge Sukruoglu; Celik, Betul; Gultaslar, Busra Kurt; Bay, Sema Buyukkapu; Tuncer, Samuray; Yazici, Hulya (Lippincott Williams and Wilkins, 2024)

  The aim of the study was to investigate the frequency and types of mutations on the retinoblastoma gene (RB1 gene) in Turkish population. RB1 gene mutation analysis was performed in a total of 219 individuals (122 probands ...

• Clarification of red grape juice by amine-functionalized magnesium silica aerogel 

  Kara, Ilkay Turhan; Yucel, Sevil; Arici, Muhammet (Elsevier Ltd, 2024)

  The clarification conditions and the selection of the clarification agent are pivotal in eliminating the haze components from red grape juice (RGJ) while minimizing the loss of functional color components. In this context, ...

• High Expression of miR-218-5p in the Peripheral Blood Stream and Tumor Tissues of Pediatric Patients with Sarcomas 

  Ozdenoglu, Fazilet Yildiz; Odemis, Demet Akdeniz; Erciyas, Seda Kilic; Tuncer, Seref Bugra; Gultaslar, Busra Kurt; Salduz, Ahmet; Buyukkapu, Sema; Olgac, Necat Vakur; Kebudi, Rejin; Yazici, Hulya (Springer, 2024)

  Sarcomas are malignant tumors that may metastasize and the course of the disease is highly aggressive in children and young adults. Because of the rare incidence of sarcomas and the heterogeneity of tumors, there is a need ...

• Comparison of microRNA expression levels in patients with schizophrenia before and after electroconvulsive therapy 

  Saglam, Nazife Gamze Usta; Duz, Mehmet Bugrahan; Yilmaz, Seda Salman; Ozen, Mustafa; Balcioglu, Ibrahim (LIPPINCOTT WILLIAMS & WILKINS, 2024)

  ObjectiveExploring the role of microRNAs in the antipsychotic efficacy of electroconvulsive therapy (ECT) will contribute to understanding the underlying mechanism through which ECT exerts its therapeutic effects. The ...

• The effects of the combination of temozolomide and Eribulin on T98G human glioblastoma cell line 

  Tanriverdi, Gamze; Kaleci, Belisa; Yavuz, Furkan; Sahin, Hakan; Purelku, Merjem; Yazici, Zeliha; Kokturk, Sibel (TAYLOR & FRANCIS INC, 2024)

  Glioblastoma tumors are the most aggressive primary brain tumors that develop resistance to temozolomide (TMZ). Eribulin (ERB) exhibits a unique mechanism of action by inhibiting microtubule dynamics during the G2/M cell ...

• Exploring Chemical Composition, Antioxidant, Enzyme Inhibitory and Cytotoxic Properties of Glaucium acutidentatum Hausskn. & Bornm. from Turkey Flora 

  Yagi, Sakina; Zengin, Gokhan; Uba, Abdullahi Ibrahim; Maciejewska-Turska, Magdalena; Sieniawska, Elwira; Swiatek, Lukasz; Rajtar, Barbara; Guler, Osman; Dall'Acqua, Stefano (MDPI, 2024)

  The present study was performed to determine the chemical constituents, cytotoxicity, antioxidant and enzyme inhibition activities of the aerial parts of Glaucium acutidentatum Hausskn. and Bornm. (family Papaveraceae). ...

• Factors associated with psychological distress during genetic counseling in high-risk women with breast cancer in Turkey 

  Anuk, Dilek; Tuncer, Seref Bugra; Ozkan, Mine; Yazici, Hulya (Springer Science and Business Media Deutschland GmbH, 2024)

  Purpose This study aims to shed light on the rather neglected area of research of psychological distress in women facing genetic counselling in Turkey, where few institutions providing such counselling exist. Methods 105 ...

• The Relationship between Frontal QRS-T Angle and Vitamin D Deficiency 

  Demir, Fulya Avci; Bingol, Gulsum; Ersoy, Ibrahim; Arslan, Akif; Ersoy, Pinar; Demir, Meltem; Unlu, Serkan (Multidisciplinary Digital Publishing Institute (MDPI), 2024)

  Background and Objectives: A deficiency in serum 25-hydroxyvitamin D levels is associated with a number of cardiovascular situations, such as high blood pressure, heart failure, atherosclerotic heart disease, and peripheral ...

• Biological, computational evaluation of novel benzofuranyl derivatives as acetylcholinesterase and butyrylcholinesterase 

  Usanmaz, Hande; Tas, Omer; Ekinci, Deniz; Uba, Abdullahi Ibrahim; Atmaca, Ufuk (Taylor and Francis Ltd., 2024)

  Aim: A highly efficient one-step method has been developed for the synthesis of benzofuranyl derivatives from 2-benzoylcyclohexane-1-carboxylic acid derivatives using chlorosulfonyl isocyanate. This novel method provides ...

• High antibiotic resistance rates in Helicobacter pylori strains in Turkey over 20 years 

  Sarikaya, Burak; Cetinkaya, Riza Aytac; Ozyigitoglu, Derya; Isik, Sinem Akkaya; Kaplan, Mustafa; Kirkik, Duygu; Gorenek, Levent (Lippincott Williams and Wilkins, 2024)

  Objective Helicobacter pylori (Hp) eradication therapy is crucial for preventing the development of gastritis, peptic ulcers, and gastric cancer. An increase in resistance against antibiotics used in the eradication of Hp ...

• Digital natives of the labor market 

  Yilmaz, Betul; Kisactutan, Elvin Dinler; Karatepe, Secil Gurun (Frontiers Media SA, 2024)

  Introduction Today's labor market is comprised of different generations and in the near future, the majority of it will consist of Generation Z. In this respect, it is of great importance to know the perspective of Generation ...

• Combining chemical profiles and biological abilities of different extracts from Tanacetum nitens ( Boiss. & NoE) Grierson using network pharmacology 

  Dall'Acqua, Stefano; Yagi, Sakina; Sut, Stefania; Uba, Abdullahi Ibrahim; Ponniya, Sathish Kumar M.; Koyuncu, Ismail; Toprak, Kenan; Balos, Mehmet Maruf; Kaplan, Alevcan; Cakilcioglu, Ugur; Zengin, Gokhan (John Wiley and Sons Inc, 2024)

  Tanacetum nitens ( Boiss. & No & euml;) Grierson is an aromatic perennial herb used in Turkish traditional medicine to treat headache, fever, and skin diseases. This study aimed to investigate the chemical composition, ...

• A Visceral Leishmaniasis Case from the Black Sea Region 

  Onec, Birguel; Ozturk, Cihadiye Elif; Yazici, Ayten (GALENOS PUBL HOUSE, 2024)

  Karadeniz Bölgesinden Bir Visseral Leishmaniasis Olgusu: Deri Lezyonları ve Kemik İliğinde Leishmania donovani Amastigotları.

• Novel benzene sulfonamide-piperazine hybrid compounds 

  Buran, Kerem; Inan, Yigit; Uba, Abdullahi Ibrahim; Zengin, Gokhan (Walter de Gruyter GmbH, 2024)

  Benzene sulfonamides are an important biological substituent for several activities. In this study, hybridization of benzene sulfonamide with piperazine derivatives were investigated for their antioxidant capacity and ...

• Effect of polycystic ovary syndrome on the life quality of young women 

  Tandogan, Ozden; Ak, Eda Yakit; Akdemir, Arzu; Oskay, Umran; Callioglu, Nihal (Associacao Medica Brasileira, 2024)

  OBJECTIVE: The study evaluated the opinions of polycystic ovary syndrome on the life quality of women. METHODS: A total of 249 women with polycystic ovary syndrome participated in this descriptive study between October ...

• Exome data of developmental and epileptic encephalopathy patients reveals de novo and inherited pathologic variants in epilepsy-associated genes 

  Capan, Ozlem Yalcin; Yapici, Zuhal; Ozbil, Mehmet; Caglayan, Hande S. (W.B. Saunders Ltd, 2024)

  Purpose: In Developmental and Epileptic Encephalopathies (DEEs), identifying the precise genetic factors guides the clinicians to apply the most appropriate treatment for the patient. Due to high locus heterogeneity, WES ...

• Exploring the composition and potential uses of four hops varieties through different extraction techniques 

  Kljakic, Aleksandra Cvetanovic; Ocvirk, Miha; Rutnik, Ksenija; Kosir, Iztok Joze; Pavlic, Branimir; Maskovic, Pavle; Maskovic, Jelena; Teslic, Nemanja; Stupar, Alena; Uba, Abdullahi Ibrahim; Zengin, Gokhan (Elsevier Ltd, 2024)

  Hydrophilic, lipophilic extracts and essential oil of four hops varieties from Slovenia were examined in this study. Lipophilic extracts were obtained by supercritical extraction (SFE), while for hydrophilic extracts ...

• miR-3653-3p Expression in PBMCs: Unveiling the Diagnostic Potential for Ovarian Cancer 

  Delek, Fatma Seher Pektopal; Tuncer, Seref Bugra; Odemis, Demet Akdeniz; Erciyas, Seda Kilic; Erdogan, ozge Sukruoglu; Saip, Pinar; Yazici, Hulya (Springer, 2024)

  Ovarian cancer is typically diagnosed at an advanced stage, recurs early and often, and currently lacks effective treatment. Therefore, overall survival and progression-free survival are relatively short for this disease. ...

• Synthesis of novel coumarin-triazole hybrids and first evaluation of the 4-phenyl substituted hybrid loaded PLGA nanoparticles delivery system to the anticancer activity 

  Arvas, Busra; Ucar, Burcu; Acar, Tayfun; Varli, Hanife Sevgi; Arvas, Melih Besir; Aydogan, Feray; Yolacan, Cigdem (Institute of Physics, 2024)

  Despite the discovery of many chemotherapeutic drugs that prevent uncontrolled cell division processes in the last century, many studies are still being carried out to develop drugs with higher anticancer efficacy and lower ...

• Evaluation of treatment outcomes and tolerability in older patients with rectal cancer treated with radiotherapy accompanied by the G-8 geriatric score: TROD13-003 multicenter study 

  Kaydihan, Nuri; BESIII Collaboration (Elsevier Ltd, 2024)

  Introduction: The choice of treatment for rectal cancer often differs in older and younger patients, with the rate of radiotherapy use lower among older adults. In our daily practice, when evaluating a frail older patient ...

Daha Fazla